We are seeking post-docs to develop hydrogels incorporating VLPs that carry medical cargos for drug delivery, immunotherapy and vaccines. Interested candidates with a background in nanotechnology, polymer chemistry or materials science, please find out more here.
We are seeking post-docs with training in molecular biology and immunology to develop mRNA vaccines and cancer immunotherapies; interested candidates, please find out more here.
We also welcome talented and motivated graduate students (PhD and Master) and undergraduate students (from Engineering or Biology) to join our projects at the interface of nanotechnology and medicine.
Lab Manager/Research Associate
We are seeking to recruit an organized Lab Manager/Research Associate. This position has dual functions of laboratory management and scientific research. To learn more about the position, see here.
Sourabh Shukla, Ph.D.
Sourabh has been a member of the Steinmetz lab since 2010. His earlier work focused on evaluation of structure-function relationships of viral nanoparticles (VNP) and developing VNP-based platform technology for drug delivery and imaging applications. His current research interest lies in development of viral nanoparticles based cancer vaccines and immunotherapies. His prior post-doctoral research training was at the Bar-Ilan University, Israel (2008-2010) working on the development of nanoparticle-based anti-viral therapies. Sourabh obtained his PhD from the National Chemical Lab in Pune, India (2007).
Christine E. Boone, M.D., Ph.D.
Christine is an Interventional Radiology (Integrated IR/DR) Resident in the Clinician-Scientist training program at UCSD. She completed MD and PhD degrees in the Medical Scientist Training Program at the Johns Hopkins School of Medicine, where she investigated in vivo perturbations of electrical activity in the hippocampus related to memory processing in a mouse model of Fragile X syndrome. Christine joined the Steinmetz Lab in 2019 as an NIH T32-pathway post-doctoral clinician-scientist trainee. Her current research focuses on developing plant virus-like particles (VLPs) as immunological adjuvants for cancer therapy. She aims to combine Interventional Radiology's strengths in minimally invasive imaging-guided disease targeting with the versatility of VLP nanotechnology to develop novel methods to treat cancer and other disorders. In her free time, Christine enjoys travel, Middle Eastern dance, surfing, and rock climbing.
Samuel Penziner, M.D.
Sam is an infectious disease fellow at UCSD interested in finding new ways to fight drug-resistant bacteria and conducts research on bacteriophages and phage therapy. He works in the labs of Robert "Chip" Schooley and David Pride but is also collaborating closely with the Steinmetz lab. He received his M.D. from NYU Medical Center in 2015 and completed his internal medicine residency at Vanderbilt University Medical Center in 2018. In his spare time Sam enjoys rock climbing, reading, pottery, and coffee.
Ted (Edward) Koellhoeffer, M.D., Ph.D.
Ted is a Diagnostic Radiology Resident in the Clinician-Scientist Scholarship Research Program (CSSRP) at UCSD. He completed his MD and PhD degrees from the Medical Scientist Training Program at the University of Texas at Houston, a joint dual-degree program at McGovern Medical School and MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences. Ted’s thesis research work investigated epigenetic molecular mechanisms of aging in microglia in the central nervous system. Ted joined the Steinmetz lab in 2020 during his first year at UCSD as part of the T32 CSSRP residency program. His current research interests include the utilization of plant viruses in immunotherapeutic treatment of cancer and other diseases. In his free time, Ted enjoys photography, going to the beach, and spending time with his family.
Mansur Ghani, MD
Mansur is an Interventional Radiology (Integrated IR/DR) Resident in the Clinician-Scientist training program at UCSD. He completed his MD at Yale School of Medicine where he investigated imaging biomarkers for treatment response in liver cancer treated with minimally-invasive, image-guided procedures. Mansur joined the Steinmetz lab in 2020 during his first year in the T32 Clinician-Scientist Radiology Residency Program through a collaborative effort with Dr. Isabel Newton to study the treatment of liver cancer with plant viruses in combination with cryoablation, an interventional radiology procedure that kills cancer cells by freezing them. Outside of the lab and his clinical work, Mansur enjoys photography, astronomy, hiking and tennis.
Oscar Ortega-Rivera, Ph.D.
Oscar is a Postdoctoral Scholar and joined the Steinmetz lab at October 2018. He received his PhD in 2017 from Autonomous University of Aguascalientes (UAA) in Mexico. His thesis focuses in immunology and VLP-based cancer immunotherapy. He was a Research Associate for 3.5 years at UAA in international projects, developing VLP-plant made vaccines and therapeutics jointly with University of California Davis and Fraunhofer-IME, respectively. His current research focuses on the development of new VLP-based vaccines for the treatment of inflammatory and cardiovascular diseases. Beyond the lab duties, he enjoys hiking, traveling, watching movies, and video games.
Soo Khim Chan, Ph.D.
Soo Khim joined the Steinmetz lab as postdoctoral scholar in early February of 2019. She obtained her bachelor degree in Technology (Bioprocess) from Universiti Sains Malaysia (USM) in 2013. Then, she continued her PhD in Institute for Research in Molecular Medicine under the guidance of Assoc. Prof. Dr. Lim Theam Soon where her thesis is focused at enzyme engineering for improved substrate specificity. During her PhD, she also dealt with sensor engineering particularly DNA and paper based sensors. After completing her PhD, she worked as a postdoc researcher for few months in her PhD lab before joining Steinmetz lab. In her spare time, she enjoys studying Japanese and watching aviation related documentaries.
Sayoni Ray, Ph.D.
Sayoni is a jointpostdoc with Prof. Steinmetz and Prof. Pokorski; she started in May 2019. Her currentresearch focus is to develop slow release vaccination technique againstinfectious disease and cancer using viral nanoparticles. Previously, she obtained Bachelor’s degree inChemistry from the University of Calcutta, India and Master’s degree from theIndian Institute of Technology (IIT), Kanpur, India. She has earned PhD from theUniversity of California, Los Angeles (UCLA), where her dissertation project focused on early tumor detection with high contrast MRI and controlled drug deliverywith online monitoring using liposomal nanoparticles. Other than research work,she spends time by reading storybooks, listening to music, watching movies andtraveling.
Christian I. Nkagna, Ph.D.
Christian is a researchPharmacist/Chemist interested in nanotechnology and formulation sciencestargeting human health. He completed his BPharm degree in 2014 at theUniversity of Kinshasa (DR Congo) and PhD in Chemistry in 2019 at RhodesUniversity (South Africa). His PhD focused on nanoscale drug delivery,exploring stimuli-responsive liposomes for controlled delivery of antimicrobialagents. Christian joined the Steinmetz lab in February 2020. His postdoc researchexplores plant viral nanoparticles as smart ‘theranostic’ platforms for targetingcancers (therapy and diagnosis). Out of the lab, Christian mostly enjoyscommunity service activities, and his own space for horror/vampire movies.
Zhongchao (Kevin) Zhao, Ph.D.
Kevin joined the Steinmetz lab as a Postdoctoral Scholar in September of 2020. He obtained his bachelor and master degrees back in China from China University of Mining and Technology, Beijing from 2007 to 2014. In August 2014, he came to US and started his PhD study in Prof. Adam Zlotnick’s lab at Indiana University. His PhD work focused on the understanding and regulating of Hepatitis B virus capsid assembly and the re-design of capsid protein and assembly pathway to create holey capsids for engineering purposes. His current research focuses on the development and engineering of CPMV viral capsids for ovarian cancer treatment. Other than research, Kevin is a big fun of sports. He likes watching NBA and NFL, also he likes playing basketball, tennis and surfing.
Adam Caparco, Ph.D.
Adam joined the Steinmetz lab in January 2021, with research focused on using plant viruses and VLPs for precision agriculture and living materials applications. Adam completed his PhD in Chemical and Biomolecular Engineering at Georgia Institute of Technology (2020) in Atlanta, GA under Profs. Julie Champion and Andreas Bommarius. His thesis work focused on enzyme immobilization and protein-inorganic material assembly. After receiving a STEM Chateaubriand Fellowship (2019), Adam also worked for several months at Genoscope in Evry, France on an enzyme discovery and metagenomics project. Prior to his thesis work, Adam studied Chemical and Biomolecular Engineering at UCLA (2015), where his undergraduate research focused on metabolic engineering. In his spare time, Adam enjoys ambitious cooking projects, video games, traveling, and volunteering with LGBTQ organizations.
Ivonne González Gamboa, Ph.D.
Ivonne began her postdoctoral research at Steinmetz Lab in January 2021. She has a bachelor degree in Biotechnology Engineering with a minor in Research and Innovation from Tecnológico de Monterrey (México). She later obtained a M.Sc. in Agrobiotechnology, as well as a Ph.D. in Plant Biotechnology, under the direction of Prof. Fernando Ponz at Universidad Politécnica de Madrid (Spain) in September 2017. Her graduate research involved the development of a plant viral platform for chemical and genetic functionalization of the TuMV coat protein. Then, she completed a postdoc appointment at the Álvarez-Trujillo Lab at Tecnológico de Monterrey, where she worked on developing chemically-modified viral nanoparticles (VNPs) as biomaterials for tissue regeneration. Her current project focuses on engineering VNPs for nanoAg applications and precision farming. Besides doing research, Ivonne loves teaching, singing and playing the guitar, as well as traveling and going to the movies with friends.
Jessica Fernanda Affonso de Oliveira, Ph.D.
Jessica Fernanda Affonso de Oliveira joined the Steinmetz lab as postdoctoral scholar in April of 2021. She obtained her bachelor’s degree in chemistry from Universidade Federal de Sao Carlos (UFSCar) in 2011. Then, she continued her Master and PhD degrees in Centro de Pesquisa em Energia e Materiais (CMPEM - Brazil) under the guidance of Prof. Dr. Mateus Borba Cardoso where her research was focused at development of tailored functional nanomaterials against resistant bacteria strains (Master) and development of selective targeting nanomateriais for cancer treatment, where she worked with Hodgkin’s Lymphomas. During her PhD, she also spent one year as a Visiting Scholar at Prof. Vicent M. Rotello lab in Amherst (UMass-Amherst), where she collaborates in several different projects. In her spare time, she loves spending time with her family, travel, studying other languages and watching funny Netflix shows.
Eunkyeong Jung, Ph.D.
Eunkyeongjoined the Steinmetz lab in April 2021. She completed M.S. and Ph.D. in Biotechnology& nanoengineering at Jeonbuk National University (South Korea) under the directionof Prof. Dongwon Lee (in February 2021). Her Ph.D. research focused on thedevelopment of pathological stimuli-responsive theranostic polymer nanoparticlesfor ROS-related diseases such as thrombosis, ischemic injury, and cancer. Outof the lab, she enjoys baking, hiking, watching K-dramas, and video chattingwith her family.
Lu is a PhD Student in Biomedical Engineering who joined the Steinmetz lab in January 2018. Lu obtained her B.S. in Biomedical Engineering and M.S. in Materials Science at Washington University in St. Louis, where she worked on preservation of gold nanoparticle based biosensors in Dr. Singamaneni's lab. She is interested in the immunotherapeutic applications of viral nanoparticles. In her spare time, Lu enjoys cooking, singing, traveling and exploring.
Matthew is a Ph.D. Student in NanoEngineering who joined the Steinmetz lab in August 2018. Matthew obtained his B.S. in Chemistry in 2016 from the University of Maryland, Baltimore County, where he conducted medicinal and polymer chemistry research. Before joining the lab, Matthew worked as a Research Assistant under the mentorship of Drs. Laura Ensign and Justin Hanes in the Center for Nanomedicine at the Johns Hopkins Wilmer Eye Institute. His research focused on engineering clinically-translatable, nano/micro-particle platforms for ocular drug delivery. His translational focus continues in the Steinmetz lab - engineering viral nanoparticle-based platforms for applications in cardiovascular drug delivery, molecular imaging, and theranostics. For leisure, Matthew enjoys golf, soccer, tennis, and photography.
Torus Washington II
Torus is a Ph.D. student in Nanoengineering who joined the Steinmetz Lab in April 2019. Torus obtained his B.S. in Materials Science & Engineering from the Georgia Institute of Technology in Atlanta, Georgia, where he worked on gold nanoparticle cancer therapeutics. Torus then obtained his M.S. in Nanotechnology from the University of Central Florida in Orlando, Florida, where he worked on photodynamic cancer therapy, fluorescence lifetime imaging of citrus greening treatment bacterial nanotherapeutics (ZinkicideTM), and fluorescence lifetime imaging-aided tracking of nanoparticle movement within plant vascular tissue. His current focus in the Steinmetz lab is the development of viral nanoparticles for immunotherapy and small molecule drug delivery. In his free time, Torus enjoys quality time with family & friends, watching and playing basketball or football, video games, watching TV shows, and watching movies.
Yvonne (Yifeng) Ma
Yvonne joined the Steinmetz lab in September 2019. Her current research focus is investigating the cancer cellular uptake of VLP and developing drug delivery system based on that. Yvonne received her B.S. in polymer science and engineering at Case Western Reserve University in 2019, where she worked on engineering polysaccharide derivatives for hemostasis augmentation. In her free time, she enjoy playing with her cats, listening to Kpop, and traveling.
Eric joined the Steinmetz lab in September 2019. His work focuses on using targeted viral plant nanoparticles as immunotherapeutics for cancer as well as developing new plant nanomedicines using layer-by-layer coatings. Eric received his B.S. in bioengineering at UCLA in 2018, where he researched using laser-generated shockwaves for bacterial biofilm debridement. When not in lab, Eric enjoys watching soccer and basketball games, hanging out with friends, and finding delicious new restaurants.
Armando is a M.S. student in Bioengineering who joined the Steinmetz lab in January 2020. He is working jointly with the Pokorski lab to develop slow-release vaccine devices. He earned his B.S. in Molecular, Cell, and Developmental Biology at UCLA in 2017. Following his studies, he worked in Dr. Robert Modlin's lab at UCLA, studying the effects of Cutibacterium acnes bacteriophages on cutaneous immune responses. Outside of lab, he likes to go to concerts and consume copious amounts of boba.
Miguel joined as a fourth year Nanoengineering undergraduate at UCSD and transitioned to be a PhD student in NanoEngineering in the Fall 2020. Miguel has a particular interest in cancer and cardiovascular research. Outside of the lab he spends his time playing baseball, video games, and spending time with his friends.
Andrea Monroy Borrego
Andrea is a Ph.D. Student in NanoEngineering, she joined the Steinmetz lab in September 2020 and obtained her B.S. in Biotechnology Engineering from Tecnológico de Monterrey, México, the same year. There she collaborated in multiple projects in the Alvarez & Trujillo Lab, specializing in the use of plant viral nanoparticles for bioprinting of dermal tissue. Andrea has collaborated in projects with Rice University on understanding autophagy of Arabidopsis thaliana, and with KAUST analyzing the effects of climate change on the red sea. Her current research focuses on engineering plant viral nanoparticles for agricultural applications. In addition, she loves rock climbing, hiking and reading batman comics.
Aayushma is a third year Bioengineering: Biotechnology undergraduate at UCSD. She enjoys working in the lab and has an interest in cancer research. Her goals are to continue research and to get a PhD. In her free time, she likes painting, watching movies, listening to music and spending time with friends and families.
Scientists and Post-docs
Alumni | CWRU
Residents and Lab Management
Craig D’Cruz (BME, Fall 2011, Spring 2012), Brian So (BME, Fall 2011, Spring 2012), Christine DeBaez (BME, Summer 2012), Josh Mealy (REU student from University of Pittsburgh, Summer 2011), Mary Ryan (Honors Student, University of Dayton,Summer 2011), Siji Oluwadara (REU student from Vanderbilt University, Summer2012), Sid (Sourav) Dey (BME, Spring 2011-Fall 2012), Samuel Alexander (BME,Spring 2011-Fall 2012), Nadia Ayat (BME, Fall 2010-Spring 2013), Kevin Chen (BME, Fall 2010-Spring 2013), Alice Yang (BME, Summer 2011-Spring 2013), Pooja Rambhia (Biochemistry, Summer 2012-Spring 2013, Co-mentor, Neil Greenspan, CWRU Pathology),
Matt Plecha (BME, Summer 2012-Spring 2013), Steven Hern (BME, Fall2011-Fall 2013), Mengzhi Wu (BME, Spring 2013-Spring 2014), John Kim (Biology,Summer 2014-Spring 2015), Nick DiFranco (BME, Spring 2014-Spring 2015), Lauren Randolph (BME, Fall 2011-Spring 2015), Paul Chariou (BME, Fall 2011-Spring 2015), Allen VanMeter (BME, Summer 2012-Spring 2015), Greg Hsu (Chemistry, Spring 2013-Spring 2015), Michael McBurney (BME, Spring 2013-Spring 2015), Diana Acosta (BME, Summer 2013-Spring2015), Adithy Nagarajan (BME, Fall 2013-Spring 2016), Katherine Krawiec (BME, Summer 2014-Spring 2016),
Slater Jameson (BME, Fall 2014-Spring 2016), Sarah Woods (BME, Summer 2014-Spring 2016), Jacob Schimelman (Macro, Summer 2012-Spring 2016), Bryce Stamp (BME, Fall 2014-Fall 2016), Jeffrey Shen (BME, Summer 2016-Fall 2016), Stephen Wang, (BME, Summer 2016-Fall 2016), Paul Lin (CSU, Fall 2016-Spring 2017), Ishan Singhal (Fall 2016-Spring 2017), Jing Pu (Fall 2016-Spring 2017), Xingjian (Jack) Gong (Fall 2015-Sprin 2018), Alan Dogan (Fall 2016-2018), Akshata Rudrapatna (Spring 2017-Spring 2018), Cian Desai (Fall 2017-Spring 2018), Alex Welsh (Fall 2017-Spring 2018).