Current Funding
OISE PIRE-1844463
PIRE: Bio-inspired materials and systems; Pilot Project: Dynamic virus crystals and hydrogels.
DMR-2134535
FMSG Bio: Rapid Biomanufacturing of mRNA Vaccines inPlant Chloroplasts. In collaboration with Giraldo (UCR) and Lowry (U Pitt).
Che-1832256
NSF Center for the Chemistry of Molecularly Optimized Networks (MONET). In collaboration with Duke and MIT.
R01CA253615
Bioprinting Plant Virus Nanoparticles for Immunotherapy and Relapse Prevention of Ovarian Cancer. In collaboration with Shaochen Chen (UCSD) and Steve Fiering (Dartmouth).
U01-R01CA274640
Toward translation of a plant virus-based in situ vaccinationnanotechnology. In collaboration with Dr. Steve Fiering, Dartmouth College and Dr. Ashish Ranjan, Oklahoma State University.
R01-CA224605
Dual-pronged chemo-immunotherapy delivered using our bio-inspired nanotechnologies. This grant was renewed!
R21-AI161306
mRNA COVID-19 Vaccines Delivered with Plant Virus/Polymer Devices in collaboration with Dr. Pokorski.
R01-HL137674
Bio-inspired nanotechnologies to aid risk stratification and therapy of deep vein thrombosis.
RSNA R&EFoundation
Novel tumor-targeted dual NIRF/MRI imaging nanoparticle for longitudinal cancer imaging. PI Krister Barkovich. Mentor: Nicole Steinmetz.
W81XWH2010742
VLP immunotherapy combined with cryoablation for liver cancer treatment, in collaboration with Drs. Newton and Webster (VA, UC San Diego).
NIFA 2022-67012-36698
Plant virus nanoparticle technology as plant vaccines; PI Caparco, Mentor: Steinmetz.
UCMEXUS-CONACYT CN-20-145
Assessment of Potyvirus-like particle antigenpayload by means of chemical coupling for enhancing the immunogenicity of Zikavirus antigen. In collaboration with GutierrezOrtega (Mexico).
Past Funding
U01-CA218292
In situ vaccination nanotechnology. In collaboration with Dr. Steve Fiering, Dartmouth College.
The University of Sydney – University of California San Diego Partnership Collaboration Awards (PCA)
In collaboration with Dr. Markus Muellner, we will develop and study synthetic virus mimics.
SIR Foundation
Noninfectious plant virus-like nanoparticles for cancer immunotherapy. PI Christine Boone, Mentor: Nicole Steinmetz.
NSF RAPID CBET-2032196
RAPID COVID-19: Metasurface Enhanced Raman Spectroscopy Platform for High-Sensitivity, Multiplexed Detection of Antibodies and RNA for Point-of-Care Diagnostics
in collaboration with Professor Andrea Tao, UCSD NanoEngineering
NSF RAPID CMMI-2027668
RAPID: Scalable Manufacturing of a Microneedle Coronavirus Vaccine Delivery System
in collaboration with Professor Jon Pokorski, UCSD NanoEngineering
UCMEXUS-CONACYT
Treatment and prevention of atherosclerosis using a plant virus-nanoparticle vaccine platform. PI Ortega-Rivera, Mentor Steinmetz
DMR-1452257 CAREER
Plant virus-based nanoparticles conjugates for medical imaging and environmental sensing
Private Donor | CWRU
Translational development of VLP immunotherapy for ovarian cancer. In collaboration with Dr. DiFeo at CWRU.
R21-EB024874
Protein/polymer devices for slow-release immunotherapy. In collaboration with Dr. Pokorski (NanoEngineering).
CDDI Pilot
Cancer immunotherapy with plant virus-based biologics. In collaboration with Dr. Gutkind, MCC.
Case-Coulter Translational Research Partnership
Translational of plant VLPs for cancer immunotherapy. PIs: Steinmetz and Kim (UH Seidman).
Team Science Award
T-cell vaccines targeting breast cancer. PI Shukla (Research Professor in the Steinmetz Lab), Co-PI Levine (MMB), and Co-I Steinmetz.
CHE-1306447
Plant virus-templated polymeric nanoparticles, in collaboration with PI Jon Pokorski (Co-PI Steinmetz).
BES DE-SC0008068
DNA and virus-programmed mesoscale assemblies, in collaboration with PI Roger French (Co-PI Steinmetz).
CMMI-1333651
Nanomanufacturing went viral. In solution modification of Janus-type bionanoparticles, in collaboration with Co-PI Gobet Advincula (CWRU Macro).
DAAD-IPID4all
Student exchange between TU Dresden in Germany and CWRU, in collaboration with Professor Rainer Jordan.
CMMI-1509232 RAPID Development of a bio-inspired probe for Ebola detection, in collaboration with Co-PI Ruth Keri (Pharmacology).
Steris Corporation for Infectious Disease (Pilot)
Purging persistant viral infection with nanoparticle 'seek and protect' therapy. Multi PIs: Steinmetz and Popkin (Dermatology).
Grant #IRG-91-022-18 (Pilot Award)
HER2 immunotherapy using a plant virus-based vaccination platform.
NIH P30 CA043703 (Pilot Award)
Multi-stage delivery of nanomaterials and their cargos targeting breast cancer. PI Steinmetz, Co-PI Keri (Pharmacology).