Current Funding
Local and Philantropy
CDDI Pilot
Cancer immunotherapy with plant virus-based biologics. In collaboration with Dr. Gutkind, MCC.
Shark Tank Award
Plant glioma in situ vaccination for glioma treatment. In collaboration with Dr. Rich, MCC.
Private Donor
Translational development of VLP immunotherapy for ovarian cancer. In collaboration with Dr. DiFeo at U Michigan.
Galvanizing Engineering in Medicine (GEM) Award
REAL-TIME monitoring of phage therapy pharmacodynamics. In collaboration with Drs. Chip Schooley and Steffanie Strathdee.
The University of Sydney – University of California San Diego Partnership Collaboration Awards (PCA)
In collaboration with Dr. Markus Muellner, we will develop and study synthetic virus mimics.
Federal and National
R01-CA224605
Dual-pronged chemo-immunotherapy delivered using our bio-inspired nanotechnologies.
R01-HL137674
Bio-inspired nanotechnologies to aid risk stratification and therapy of deep vein thrombosis.
U01-CA218292
In situ vaccination nanotechnology. In collaboration with Dr. Steve Fiering, Dartmouth College.
R21-EB024874
Protein/polymer devices for slow-release immunotherapy. In collaboration with Dr. Pokorski, CWRU (contact PI).
R01-CA202814
Minimally invasive molecular imaging approaches using plant virus-based contrast agents to aid prostate cancer risk stratification.
128319-RSG-15-144-01-CDD
Filamentous plant viruses as carriers for targeted drug delivery treating triple negative breast cancer.
DMR-1452257 CAREER
Plant virus-based nanoparticles conjugates for medical imaging and environmental sensing.
Past Funding
R21-HL121130
Plant virus-based nanoparticle drug delivery targeting thrombosis.
R21-EB020946
Plant virus-based contrast agent for MRI imaging applications.
Case-Coulter Translational Research Partnership
Translational of plant VLPs for cancer immunotherapy. PIs: Steinmetz and Kim (UH Seidman).
CCR14298962
A plant virus-based breast cancer vaccine.
Team Science Award
T-cell vaccines targeting breast cancer. PI Shukla (Research Professor in the Steinmetz Lab), Co-PI Levine (MMB), and Co-I Steinmetz.
CHE-1306447
Plant virus-templated polymeric nanoparticles, in collaboration with PI Jon Pokorski (Co-PI Steinmetz).
R03-EB020602
Engineering novel filamentous plant viruses for cancer imaging and therapy
Council to Advance Human Health
Virus-based in situ vaccination: understanding the underlying mechanism.
BES DE-SC0008068
DNA and virus-programmed mesoscale assemblies, in collaboration with PI Roger French (Co-PI Steinmetz).
CMMI-1333651
Nanomanufacturing went viral. In solution modification of Janus-type bionanoparticles, in collaboration with Co-PI Gobet Advincula.
DAAD-IPID4all
Student exchange between TU Dresden in Germany and CWRU, in collaboration with Professor Rainer Jordan.
National Research Foundation
Grapevine virus targeting prostate cancer, in collaboration with the Vitis Lab at Stellenbosch University, South Africa (Professor Johan Burger and Dr. Hano Maree).
CMMI-1509232 RAPID Development of a bio-inspired probe for Ebola detection, in collaboration with Co-PI Ruth Keri.
K99/R00 EB009105
Plant virus-based nanoparticles for imaging and therapy.
14GRNT19890005
Plant virus-based nanoparticle drug delivery targeting thrombosis.
Ohio Cancer Research Associates
Plant virus drug delivery targeting breast cancer.
Steris Corporation for Infectious Disease (Pilot)
Purging persistant viral infection with nanoparticle 'seek and protect' therapy. Multi PIs: Steinmetz and Popkin (Dermatology).
Grant #IRG-91-022-18 (Pilot Award)
HER2 immunotherapy using a plant virus-based vaccination platform.
NIH P30 CA043703 (Pilot Award)
Multi-stage delivery of nanomaterials and their cargos targeting breast cancer. PI Steinmetz, Co-PI Keri.
Interdisciplinary Alliance Investment Grant (IAIG): Innovation Pilot Grant
Core-shell nanoparticles for image-guided therapy. Multi-PI collaboration: Steinmetz and Samia (Chemistry)