Current Funding
OISE PIRE-1844463
PIRE: Bio-inspired materials and systems; Pilot Project: Dynamic virus crystals and hydrogels.
DMR-2134535
FMSG Bio: Rapid Biomanufacturing of mRNA Vaccines inPlant Chloroplasts. In collaboration with Giraldo (UCR) and Lowry (U Pitt).
Che-1832256
NSF Center for the Chemistry of Molecularly Optimized Networks (MONET). In collaboration with Duke and MIT.
GalvanizingEngineering in Medicine (GEM) Award.
Plant viruses against Head and Neck Cancer. In collaboration with Dr. Ezra Cohen.
R01CA253615
Bioprinting Plant Virus Nanoparticles for Immunotherapy and Relapse Prevention of Ovarian Cancer. In collaboration with Shaochen Chen (UCSD) and Steve Fiering (Dartmouth).
U01-R01CA274640
Toward translation of a plant virus-based in situ vaccinationnanotechnology. In collaboration with Dr. Steve Fiering, Dartmouth College and Dr. Ashish Ranjan, Oklahoma State University.
R01-CA224605
Dual-pronged chemo-immunotherapy delivered using our bio-inspired nanotechnologies. This grant was renewed!
R01-CA202814
Minimally invasive molecular imaging approaches using plant virus-based contrast agents to aid prostate cancer risk stratification
R21-AI161306
mRNA COVID-19 Vaccines Delivered with Plant Virus/Polymer Devices in collaboration with Dr. Pokorski.
R01-HL137674
Bio-inspired nanotechnologies to aid risk stratification and therapy of deep vein thrombosis.
RSNA R&EFoundation
Novel tumor-targeted dual NIRF/MRI imaging nanoparticle for longitudinal cancer imaging. PI Krister Barkovich. Mentor: Nicole Steinmetz.
Sponsored Research
Sponsored research agreement with AMAT on coated plant virus nanotechnology
W81XWH2010742
VLP immunotherapy combined with cryoablation for liver cancer treatment, in collaboration with Drs. Newton and Webster (VA, UC San Diego).
NIFA-2020-67021-31255
Plant virus-like nanopesticides for precision farming.
NIFA 2022-67012-36698
Plant virus nanoparticle technology as plant vaccines; PI Caparco, Mentor: Steinmetz.
CARA agreement
Sponsored research agreement with BASF on plant virus-based agrochemicals
UCMEXUS-CONACYT CN-20-145
Assessment of Potyvirus-like particle antigenpayload by means of chemical coupling for enhancing the immunogenicity of Zikavirus antigen. In collaboration with GutierrezOrtega (Mexico).
Shaughnessy Family Fund for Nano-ImmunoEngineering
Treatment and prevention of ovarian cancer.
Past Funding
U01-CA218292
In situ vaccination nanotechnology. In collaboration with Dr. Steve Fiering, Dartmouth College.
The University of Sydney – University of California San Diego Partnership Collaboration Awards (PCA)
In collaboration with Dr. Markus Muellner, we will develop and study synthetic virus mimics.
SIR Foundation
Noninfectious plant virus-like nanoparticles for cancer immunotherapy. PI Christine Boone, Mentor: Nicole Steinmetz.
NSF RAPID CBET-2032196
RAPID COVID-19: Metasurface Enhanced Raman Spectroscopy Platform for High-Sensitivity, Multiplexed Detection of Antibodies and RNA for Point-of-Care Diagnostics
in collaboration with Professor Andrea Tao, UCSD NanoEngineering
NSF RAPID CMMI-2027668
RAPID: Scalable Manufacturing of a Microneedle Coronavirus Vaccine Delivery System
in collaboration with Professor Jon Pokorski, UCSD NanoEngineering
UCMEXUS-CONACYT
Treatment and prevention of atherosclerosis using a plant virus-nanoparticle vaccine platform. PI Ortega-Rivera, Mentor Steinmetz
128319-RSG-15-144-01-CDD
Filamentous plant viruses as carriers for targeted drug delivery treating triple negative breast cancer.
DMR-1452257 CAREER
Plant virus-based nanoparticles conjugates for medical imaging and environmental sensing
UCOP-R00RG2471
Improved detection of COVID-19 through bioinspired diagnostics
NIFA-SBIR 2019-33610-29873
collaborative research with BioProdex Inc.
Galvanizing Engineering in Medicine (GEM) Award
Real-time monitoring of phage therapy pharmacodynamics. In collaboration with Drs. Chip Schooley and Steffanie Strathdee (IPATH).
Private Donor | CWRU
Translational development of VLP immunotherapy for ovarian cancer. In collaboration with Dr. DiFeo at CWRU.
R21-EB024874
Protein/polymer devices for slow-release immunotherapy. In collaboration with Dr. Pokorski (NanoEngineering).
CDDI Pilot
Cancer immunotherapy with plant virus-based biologics. In collaboration with Dr. Gutkind, MCC.
Shark Tank Award
Plant glioma in situ vaccination for glioma treatment. In collaboration with Dr. Rich, MCC.
R21-HL121130
Plant virus-based nanoparticle drug delivery targeting thrombosis.
R21-EB020946
Plant virus-based contrast agent for MRI imaging applications.
Case-Coulter Translational Research Partnership
Translational of plant VLPs for cancer immunotherapy. PIs: Steinmetz and Kim (UH Seidman).
CCR14298962
A plant virus-based breast cancer vaccine.
Team Science Award
T-cell vaccines targeting breast cancer. PI Shukla (Research Professor in the Steinmetz Lab), Co-PI Levine (MMB), and Co-I Steinmetz.
CHE-1306447
Plant virus-templated polymeric nanoparticles, in collaboration with PI Jon Pokorski (Co-PI Steinmetz).
R03-EB020602
Engineering novel filamentous plant viruses for cancer imaging and therapy
Council to Advance Human Health
Virus-based in situ vaccination: understanding the underlying mechanism.
BES DE-SC0008068
DNA and virus-programmed mesoscale assemblies, in collaboration with PI Roger French (Co-PI Steinmetz).
CMMI-1333651
Nanomanufacturing went viral. In solution modification of Janus-type bionanoparticles, in collaboration with Co-PI Gobet Advincula (CWRU Macro).
DAAD-IPID4all
Student exchange between TU Dresden in Germany and CWRU, in collaboration with Professor Rainer Jordan.
National Research Foundation
Grapevine virus targeting prostate cancer, in collaboration with the Vitis Lab at Stellenbosch University, South Africa (Professor Johan Burger and Dr. Hano Maree).
CMMI-1509232 RAPID Development of a bio-inspired probe for Ebola detection, in collaboration with Co-PI Ruth Keri (Pharmacology).
K99/R00 EB009105
Plant virus-based nanoparticles for imaging and therapy.
14GRNT19890005
Plant virus-based nanoparticle drug delivery targeting thrombosis.
Ohio Cancer Research Associates
Plant virus drug delivery targeting breast cancer.
Steris Corporation for Infectious Disease (Pilot)
Purging persistant viral infection with nanoparticle 'seek and protect' therapy. Multi PIs: Steinmetz and Popkin (Dermatology).
Grant #IRG-91-022-18 (Pilot Award)
HER2 immunotherapy using a plant virus-based vaccination platform.
NIH P30 CA043703 (Pilot Award)
Multi-stage delivery of nanomaterials and their cargos targeting breast cancer. PI Steinmetz, Co-PI Keri (Pharmacology).
Interdisciplinary Alliance Investment Grant (IAIG): Innovation Pilot Grant
Core-shell nanoparticles for image-guided therapy. Multi-PI collaboration: Steinmetz and Samia (Chemistry).