Current Funding

OISE PIRE-1844463

PIRE: Bio-inspired materials and systems; Pilot Project:  Dynamic virus crystals and hydrogels.

DMR-2134535 

FMSG Bio: Rapid Biomanufacturing of mRNA Vaccines inPlant Chloroplasts. In collaboration with Giraldo (UCR) and Lowry (U Pitt). 

Che-1832256   

NSF Center for the Chemistry of Molecularly Optimized Networks (MONET). In collaboration with Duke and MIT.

R01CA253615

 Bioprinting Plant Virus Nanoparticles for Immunotherapy and Relapse Prevention of Ovarian Cancer.  In collaboration with Shaochen Chen (UCSD) and Steve Fiering (Dartmouth).

U01-CA218292    

In situ vaccination nanotechnology.   In collaboration with Dr. Steve Fiering, Dartmouth College. 

R01-CA224605

Dual-pronged chemo-immunotherapy delivered using our bio-inspired nanotechnologies.

R01-CA202814 

Minimally invasive molecular imaging approaches using plant virus-based contrast agents to aid prostate cancer risk stratification

R21AI161306

mRNA COVID-19 Vaccines Delivered with Plant Virus/Polymer Devices in collaboration with Dr. Pokorski.

R01-HL137674

Bio-inspired nanotechnologies to aid risk stratification and therapy of deep vein thrombosis.

W81XWH2010742         

VLP immunotherapy combined with cryoablation for liver cancer treatment, in collaboration with Drs. Newton and Webster (VA, UC San Diego).

NIFA-2020-67021-31255

Plant virus-like nanopesticides for precision farming.

128319-RSG-15-144-01-CDD 

Filamentous plant viruses as carriers for targeted drug delivery treating triple negative breast cancer.

CARA agreement 

Sponsored research agreement with BASF on plant virus-based agrochemicals

SIR Foundation

Noninfectious plant virus-like nanoparticles for cancer immunotherapy

PI Christine Boone, Mentor: Nicole Steinmetz

Shaughnessy Family Fund for Nano-ImmunoEngineering

Treatment and prevention of ovarian cancer.

The University of Sydney – University of California San Diego Partnership Collaboration Awards (PCA)

In collaboration with Dr. Markus Muellner, we will develop and study synthetic virus mimics.

UCMEXUS-CONACYT  CN-20-145

Assessment of Potyvirus-like particle antigenpayload by means of chemical coupling for enhancing the immunogenicity of Zikavirus antigen. In collaboration with GutierrezOrtega (Mexico).


Past Funding

NSF RAPID CBET-2032196

RAPID COVID-19: Metasurface Enhanced Raman Spectroscopy Platform for High-Sensitivity, Multiplexed Detection of Antibodies and RNA for Point-of-Care Diagnostics

in collaboration with Professor Andrea Tao, UCSD NanoEngineering

NSF RAPID CMMI-2027668

RAPID: Scalable Manufacturing of a Microneedle Coronavirus Vaccine Delivery System

in collaboration with Professor Jon Pokorski, UCSD NanoEngineering

UCMEXUS-CONACYT

Treatment and prevention of atherosclerosis using a plant virus-nanoparticle vaccine platform. PI Ortega-Rivera, Mentor Steinmetz

DMR-1452257 CAREER

Plant virus-based nanoparticles conjugates for medical imaging and environmental sensing

UCOP-R00RG2471

Improved detection of COVID-19 through bioinspired diagnostics

NIFA-SBIR 2019-33610-29873         

collaborative research with BioProdex Inc.

Galvanizing Engineering in Medicine (GEM) Award

Real-time monitoring of phage therapy pharmacodynamics. In collaboration with Drs. Chip Schooley and Steffanie Strathdee (IPATH).

Private Donor | CWRU

Translational development of VLP immunotherapy for ovarian cancer. In collaboration with Dr. DiFeo at CWRU.

R21-EB024874

Protein/polymer devices for slow-release immunotherapy.  In collaboration with Dr. Pokorski (NanoEngineering).

CDDI Pilot

Cancer immunotherapy with plant virus-based biologics. In collaboration with Dr. Gutkind, MCC.

Shark Tank Award 

Plant glioma in situ vaccination for glioma treatment. In collaboration with Dr. Rich, MCC.

R21-HL121130

Plant virus-based nanoparticle drug delivery targeting thrombosis.

R21-EB020946

Plant virus-based contrast agent for MRI imaging applications.

Case-Coulter Translational Research Partnership 

Translational of plant VLPs for cancer immunotherapy. PIs: Steinmetz and Kim (UH Seidman).

CCR14298962 

A plant virus-based breast cancer vaccine.

Team Science Award

T-cell vaccines targeting breast cancer. PI Shukla (Research Professor in the Steinmetz Lab), Co-PI Levine (MMB), and Co-I Steinmetz.

CHE-1306447 

Plant virus-templated polymeric nanoparticles, in collaboration with PI Jon Pokorski (Co-PI Steinmetz).

R03-EB020602 

Engineering novel filamentous plant viruses for cancer imaging and therapy

Council to Advance Human Health

Virus-based in situ vaccination: understanding the underlying mechanism.

BES DE-SC0008068 

DNA and virus-programmed mesoscale assemblies, in collaboration with PI Roger French (Co-PI Steinmetz).

CMMI-1333651 

Nanomanufacturing went viral. In solution modification of Janus-type bionanoparticles, in collaboration with Co-PI Gobet Advincula (CWRU Macro).

DAAD-IPID4all 

Student exchange between TU Dresden in Germany and CWRU, in collaboration with Professor Rainer Jordan.


National Research Foundation 

Grapevine virus targeting prostate cancer, in collaboration with the Vitis Lab at Stellenbosch University, South Africa (Professor Johan Burger and Dr. Hano Maree).

CMMI-1509232 RAPID Development of a bio-inspired probe for Ebola detection, in collaboration with Co-PI Ruth Keri (Pharmacology).

K99/R00 EB009105 

Plant virus-based nanoparticles for imaging and therapy.

14GRNT19890005

Plant virus-based nanoparticle drug delivery targeting thrombosis.

Ohio Cancer Research Associates 

Plant virus drug delivery targeting breast cancer.

Steris Corporation for Infectious Disease (Pilot)

Purging persistant viral infection with nanoparticle 'seek and protect' therapy. Multi PIs: Steinmetz and Popkin (Dermatology).

Grant #IRG-91-022-18 (Pilot Award)

HER2 immunotherapy using a plant virus-based vaccination platform.

NIH P30 CA043703 (Pilot Award) 

Multi-stage delivery of nanomaterials and their cargos targeting breast cancer. PI Steinmetz, Co-PI Keri (Pharmacology).

Interdisciplinary Alliance Investment Grant (IAIG): Innovation Pilot Grant

Core-shell nanoparticles for image-guided therapy. Multi-PI collaboration: Steinmetz and Samia (Chemistry).

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